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[Body Builder]

Sorry man, but you know we can't really trust the opinions of people who have done LL about potential LL alternatives, right?

For sure we can't trust people who believe in miracles and magic pills to get taller compared to veterans who did what they have to to get taller.

I am starting to think that you are mentally unstable because you are really frustrated about your height (we had almost the same height so I truly understand you) but at the same time you are too scared to do LL and you keep believing bs hoping that one day you'll get taller by a miracle or a pill or an injection or something easy like that.
In reality, you'll stay in misery for your whole life because there won't be an alternative until you get so old to not even care about height but to just stay alive.

Wake up dude, LL nowadays is safer than ever. Its a pity to be in a so messed up situation due to being in a height that you hate, without doing something real about that.
I hope one day you'll understand before its too late.

[F_99]

Hi O_99,

Thanks a lot for sharing these links. I'm going to have a look at them now.

Yo, np.
I actually asked him a question, but you posted it already above. He mentioned rapamycin before, so I wonder if he knows anything about the c60 fullerene, because it belongs to the 'anti-senesence' field too.

Have you ever experimented with this fullerene (c60)?

https://onlinelibrary.wiley.com/doi/full/10.1002/art.22917
(http://www.limblengtheningforum.com/index.php?topic=65449.0)

I'm wondering if it can not only prevent cartilage degenaration but also ''reverse'' it, causing articular cartilage regenaration/regrowth hence resulting in greater total leg length, but couldn't find anything

This sub topic is Limb Lengthening Surgery > Limb Lengthening Discussions

Offtopic exists, suck each other's penises there maybe

That's not what you said originally.
This topic is about the future of limb lenghtening + what do you hope to see happen, not strictly about the future of the surgery, so you can ask the original poster why they put it in the LLS sub-board.

[ghkid2019]

Brondo!!! Why u do this??? Man u is no goodie!! Goddamit brondo why daddy you mis post wrong area sir!!! I can't beliebe dis. Am in shambels rn. Me depreshun now fuk man I hate dis!!!1!!1! Brondo why u betray me Mr. Siddhartha?

[Antoine]

Joking aside, if we have to think about the future of limb lengthening, I’d say that Dr. Michael J. Assayag MD’s take shows adherence to reality but also the lack of effort to try out new things and to cooperate with other doctors and researchers in order to make cosmetic limb lengthening a really comfortable and bearable surgery. This lack of effort is the biggest issue of cll.
So, I hope that both of these scenarios will come true.
1)Completely revised limb lengthening surgery: laser osteotomy (https://aot.swiss/en/carlo/), distraction performed in a non-invasive/minimally invasive way by nanobots or something like that (no nails, no metal implants, no Ilizarov apparatus), stem cells that allow bones, tendons and muscles to stretch and regenerate easily, safely and quickly.
2)Creation and implantation of artificial growth plates that allow long bones to grow longitudinally again, as during puberty. Many research projects came very neat to this, as links below show. If this kind of research had been heavily funded, we could have had artificial growth plates implanted in our bones yet.

https://www.researchgate.net/publication/298275420_Construction_of_artificial_epiphyseal_plate_using_epiphyseal_plate_chondrocytes_of_rabbits_and_combined_scaffold
https://www.physoc.org/abstracts/enlargement-of-growth-plate-chondrocytes-in-agarose-culture/
https://www.unmc.edu/news.cfm?match=20659
https://www.semanticscholar.org/paper/Growth-Plate-Regeneration-Using-Polymer-Based-Clark/75a843c9d4887d883d4ca7b75208b18dabb02a33
https://www.eurekalert.org/pub_releases/2020-05/tifb-csa051920.php

[Drop-Loud]

Hi O_99,

Good Idea to ask him about fullerene (c60). Maybe he will have more scientific info about it. I think we could give it a try as it is safe and easy to find.

Hi Antoine,

I think most LL surgerons don't want to loose time, effort and money to find new solutions. They make enough money with actual technology. I think all people across the globe looking to increase their height with newer techniques should unit themselves to fund research.

[Drop-Loud]

Another great post about growth plates

https://www.tapatalk.com/groups/lsjl/the-most-important-topic-in-growth-plate-reopening-t1029.html

[F_99]

Nanobots to perform distraction osteogenesis are decades away at best; Unfortunately, wishful thinking.

Hi O_99,

Good Idea to ask him about fullerene (c60). Maybe he will have more scientific info about it. I think we could give it a try as it is safe and easy to find.

Hey, yes.
He's still confident about the LPP thing (in theory), inject it locally (knee) because there is so little that can enter cartilage after you become an adult.
We need test results though.

[..]

For sure we can't trust people who believe in miracles and magic pills to get taller compared to veterans who did what they have to to get taller.

I am starting to think that you are mentally unstable because you are really frustrated about your height (we had almost the same height so I truly understand you) but at the same time you are too scared to do LL and you keep believing bs hoping that one day you'll get taller by a miracle or a pill or an injection or something easy like that.
In reality, you'll stay in misery for your whole life because there won't be an alternative until you get so old to not even care about height but to just stay alive.

Wake up dude, LL nowadays is safer than ever. Its a pity to be in a so messed up situation due to being in a height that you hate, without doing something real about that.
I hope one day you'll understand before its too late.

Look mate, if you have some problem with me then just insult me straight up instead of being passive-aggressive about it and indirectly alluding to me using idiotic beat-around-the-bush terminology like this. It's laughable to call someone a coward when you do this.

I honestly don't give a sh*t about Stryde. Is it an improvement to the distraction osteogenesis technique? Sure. But it doesn't solve my (and many other people's) problems with distraction osteogenesis, which is the permanent loss of athletic ability and the risk of permanent complications. Both those problems still exist and you stand a very real chance of facing them whether you go to Dr. Paley or "Sarin the butcher" as you like to call him.

It's not a matter of pain or death. I'm not the least bit afraid of either. If these were the only "risks" implicated in CLL, I would be first in line to get it done. I need my athletic ability and cannot afford to have it hampered, which is why CLL is not an acceptable proposition for me. Plenty of others are in the same boat. Still others are not okay with risking ending up like one of the several posters (such as unicorn) whose lives were ruined by distraction osteogenesis.

Despite the fact that I regularly speak about attraction and its ramifications on this board, I'm not interested in getting taller so I can attract women. I'm not interested in sxx or relationships and haven't been for a long time. Getting taller is purely about overcoming my PHYSICAL (and to a lesser extent, social and workplace) limitations, not about peacking.

You look like a luddite imbecile when you spout garbage about "miracles" and "fairy tales" regarding novel technologies. If you don't understand the science, why criticize it? Especially when the relevant technology ALREADY EXISTS (induced Pluripotent Stem Cells) and the principal part of the procedure (generation and implantation of artificial epiphyseal cartilage) has ALREADY BEEN DONE and successfully shown to work in animal models.

If your problems with your height were purely about attracting women then sure, CLL can fix it for you. Get it done and move on. Back to your squat rack to cope with your bullsh*t weights.

[Body Builder]

A weirdo who didn't know why he even wanted to become taller and had absolutely no will to get taller.
I am sure he still moans and looks for magic pills like you while living in misery.

[F_99]

A weirdo who didn't know why he even wanted to become taller and had absolutely no will to get taller.

"..But I'm a creep, I'm a weirdo.
 What the hell I'm doing here?
 I don't belong here.."

[F_99]

From another interesting* post link from him he shared (new): **

*Possibly useful information; links might already have been posted.

** (new one): https://www.reddit.com/r/Peptides/comments/iyjn9o/a_general_list_of_peptides_plus_peptides_you/


1. -Self-improvement;Antarctic krill peptides (AKP) 
https://www.eurekaselect.com/182760/article (but on young mice; 3wks/old)

->AKPs significantly increased the longitudinal bone growth and improved bone strength. In addition, AKPs remarkably promoted proliferation and hypertrophy of chondrocytes in the growth plate.


2. -Self-improvement;ASB20123
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386482/ (on 8wks/old rats; rats stop growing at 7-8mnths/old)
https://pubmed.ncbi.nlm.nih.gov/31509532/ (12 mnths/old rats; not sure why it says with a little epiphyseal plate)

->It potently stimulated skeletal growth in rats in a dose-dependent manner, and sc infusion was more effective than bolus injection at the same dose.


3. 8-Nitro-cGMP promotes bone growth through expansion of growth plate cartilage
https://www.sciencedirect.com/science/article/abs/pii/S0891584917305956?via%3Dihub


4. A newly discovered stem cell that keeps bones growing
https://www.nature.com/articles/d41586-019-00527-w?utm_source=fbk_nnc&utm_medium=social&utm_campaign=naturenews&sf209700336=1


5. -Cosmetic, Healing;NHGFVVEVTNHGFVVEVT 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457080/ (bone renegeration; not sure about this one)
is one of the few selected as osteogenic-enhancing peptides with both the ability for osteogenic cell-selective proliferation and osteogenic differentiation. These results indicate that osteogenic-enhancing peptides are derived from BMP sequences according to the original peptide array method developed in the present study.


6. -Hormonal;PTH
https://link.springer.com/article/10.1007/s007740200011 (Human PTH (1–34) induces longitudinal bone growth in rats; relatively old)

->A stimulatory role for PTH 1-34 on tendon-to-bone healing was first suggested by Rodeo et al. who reported increased bone and fibrocartilage formation after recombinant parathyroid hormone (rhPTH) treatment in a rat rotator cuff model. Additionally, we found that there was a significant increase in the mineralization of the subchondral bone, as determined by alizarin complexone labeling, in the I-PTH group.


7. -Self-improvement;Link protein N-terminal peptide (LPP or Link N)
https://www.sciencedirect.com/science/article/abs/pii/S0003986100917582
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831317/ (1)
https://febs.onlinelibrary.wiley.com/doi/full/10.1111/j.1432-1033.1993.tb17636.x (old) (2)

->Stimulated the proliferation of Cartilage Stem/Progenitor Cells (CSPC) and accelerated the site-directional migration. Higher expression of SOX9, collagen II, and aggrecan were demonstrated in CSPCs treated with LPP. Data suggest that LPP may be a useful therapeutic substitute for direct BMP administration to treat IVD degeneration and to ameliorate IVD-associated chronic low back pain.
It's proposed that this peptide, along with several other compounds, might increase adult height.

(1) Conclusion. LPP showed application prospect in cartilage regeneration medicine by stimulating proliferation, migration, and chondrogenic differentiation of cartilage stem/progenitor cells.

(2) Since a proportion of the link protein extracted from human and pig cartilage has already undergone proteolysis to remove peptides from its N‐terminal region, these peptides may be produced in articular cartilage during the normal process of turnover and ageing.

+

-PTD-DBM since this peptide is a CXXC5 inhibitor, it might help with longitudinal bone growth
https://www.life-science-alliance.org/content/lsa/2/2/e201800254.full.pdf

-IGF-2 for longitudinal bone growth
https://pubmed.ncbi.nlm.nih.gov/20499340/
https://pubmed.ncbi.nlm.nih.gov/25910049/

[Drop-Loud]

Hi O_99,

Thank you so much for sharing all this links. It's very promising. Great job!

[ghkid2019]

Literally only 4 is relevant lol. Fück is this shīt we don't need another form of hgh

[Drop-Loud]

The most interesting finding would be these ones for people who want to grow taller. Maybe some specialists could confirm :


4. A newly discovered stem cell that keeps bones growing
https://www.nature.com/articles/d41586-019-00527-w?utm_source=fbk_nnc&utm_medium=social&utm_campaign=naturenews&sf209700336=1


7. -Self-improvement;Link protein N-terminal peptide (LPP or Link N)
https://www.sciencedirect.com/science/article/abs/pii/S0003986100917582
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831317/ (1)
https://febs.onlinelibrary.wiley.com/doi/full/10.1111/j.1432-1033.1993.tb17636.x (old) (2)

->Stimulated the proliferation of Cartilage Stem/Progenitor Cells (CSPC) and accelerated the site-directional migration. Higher expression of SOX9, collagen II, and aggrecan were demonstrated in CSPCs treated with LPP. Data suggest that LPP may be a useful therapeutic substitute for direct BMP administration to treat IVD degeneration and to ameliorate IVD-associated chronic low back pain.
It's proposed that this peptide, along with several other compounds, might increase adult height.

(1) Conclusion. LPP showed application prospect in cartilage regeneration medicine by stimulating proliferation, migration, and chondrogenic differentiation of cartilage stem/progenitor cells.

(2) Since a proportion of the link protein extracted from human and pig cartilage has already undergone proteolysis to remove peptides from its N‐terminal region, these peptides may be produced in articular cartilage during the normal process of turnover and ageing.


antarctic krill akp seems to work like indirubin if I'm right?

[F_99]

Literally only 4 is relevant lol. Fück is this shīt we don't need another form of hgh

For the adults whom had their growth plates closed we need to proliferate not only their existing chondrocytes , but also their dormant chondrocyte stem cells which LPP (Link protein N-terminal peptide) holds a lot of promise to achieve. LPP has been tested on vitro/vivo (https://www.hindawi.com/journals/sci/2018/3217895/
https://onlinelibrary.wiley.com/doi/abs/10.1002/1529-0131(199801)41:1%3C157::AID-ART19%3E3.0.CO;2-J)
and human type II collagen cells (https://onlinelibrary.wiley.com/doi/abs/10.1002/1529-0131(199801)41:1%3C157::AID-ART19%3E3.0.CO;2-J) with positive results.

Hi O_99,

Thank you so much for sharing all this links. It's very promising. Great job!

Hey, by the way what's up with this? https://www.tapatalk.com/groups/lsjl/viewtopic.php?p=8384#p8384

[ghkid2019]

Kill this topic alrdy lol. Keep believing your ossified growth plate area still contains anything but bone. "Dormant chondrocytes" lul

[F_99]

Kill this topic alrdy lol. Keep believing your ossified growth plate area still contains anything but bone. "Dormant chondrocytes" lul

I'd rather take into consideration what biohackers think could be possible for height increase on adults than an internet kid's opinion.

[ghkid2019]

Your so called biohacker doesn't even know what lyophilized powder or refrigeration is and thus rejects HGH and used 30 different peptides that does the same shiet because "muh HGH no stable"

[F_99]

Your so called biohacker doesn't even know what lyophilized powder or refrigeration is and thus rejects HGH and used 30 different peptides that does the same shiet because "muh HGH no stable"

Who cares? You're calling hypothetical solutions irrelavant without even reading into them.

[ghkid2019]

Ye mb. Just wanna see more growth plate regeneration things, rather than just stuff that works in existing growth plate. Who knows hopefully we will get stem cell injection and work from there

[Drop-Loud]

Hey, by the way what's up with this? https://www.tapatalk.com/groups/lsjl/viewtopic.php?p=8384#p8384

Hi O_99,

It's similare to this I think :

https://www.mirror.co.uk/news/uk-news/could-height-enhancing-a-grow-bics-workout-really-1332212

Some people who tried it say it works, some don't. You need to live in the UK to be able to beneficiate from it.

Otherwise, I don't know much about this "Height Increase Project 2020 Telegram Group" and I don't know how they are organized. I will try to know more.

[F_99]

Yeah, I was talking about the stretching for hours thing. That Ukrainian guy mentioned used to do something similar. Scam/spine temporary height increase looks like.   

[Drop-Loud]

An other interesting post about creating artificial growth plates : https://www.tapatalk.com/groups/lsjl/viewtopic.php?p=8456#p8456

[Drop-Loud]

Yeah, I was talking about the stretching for hours thing. That Ukrainian guy mentioned used to do something similar. Scam/spine temporary height increase looks like.   

I'm a bit skeptical about stretching. You will gain temporary height I think and not very much.

[..]

Hi O_99,

It's similare to this I think :

https://www.mirror.co.uk/news/uk-news/could-height-enhancing-a-grow-bics-workout-really-1332212

Some people who tried it say it works, some don't. You need to live in the UK to be able to beneficiate from it.

A-Grow-Bics no longer uses The Stretch Rack. They claim that inversion is far more effective.

[F_99]

Thanks yeah I have a few interesting ideas. I'm gonna try to see if I can make a video on that soon

So you did make a video. Nice.


First time I hear about this: LIPUS technology (which is low-intensity pulsed ultrasound) and how it could stimulate bone growth as some studies have been noted in jaw bones of rats.
Interesting.

Also the company BGRI reached out to you and wrote a guest article? (Part II of this blog post)
https://cyborg4life.com/future-alternatives-to-limb-lengthening-surgery/

The guy who's also commeting at the end (Harald Oberlaender) funded "Biomedical Growth Research Initiative" (BGRI):
http://www.limblengtheningforum.com/index.php?topic=5139.0

He's still on this forum, last time active, yesterday http://www.limblengtheningforum.com/index.php?action=profile;u=5003

[Drop-Loud]

Very Interesting post, thanks for sharing.

The only between rats and us is that their growth plates never close. I don't know if it's the same for rabbits.

[Drop-Loud]

For those interested, Dr. Dror Paley is the First Surgeon in the World to Perform a New Limb Lengthening Procedure with the PRECICE™ Plate Implant at St. Marys Medical Center & the Palm Beach Childrens Hospital

https://www.palmbeachchildrenshospital.com/news/newsroom/dr-dror-paley-is-the-first-surgeon-in-the-world-to-perform-a-new-limb-lengthening-procedure-with-the-precice-plate-implant-at-st-marys-medical-center-the-palm-beach-childrens-hospital

[ghkid2019]

It is very good for children, no more long time in external fixator needed for leg length discrepancy and can fix it without shoving a rod in to disturb growth plate.

The best thing is the no more external needed for kids. A kid doesn't have to deal with all that scary stuff.

[Drop-Loud]

IGF2 is very likely able to form new growth plates

https://www.naturalheightgrowth.com/2013/11/19/igf2/

https://www.tapatalk.com/groups/lsjl/continue-investigation-t1006.html#p7491

https://www.tapatalk.com/groups/lsjl/growth-taller-investigation-t1004.html#p7466



 Load-Driven Bone Lengthening

https://grantome.com/grant/NIH/R03-AR055322-01A1

https://projectreporter.nih.gov/project_info_description.cfm?aid=7670257


Patent application title: Bone Growth Compositions and Methods

http://www.patentsencyclopedia.com/app/20120276204

http://www.patentsencyclopedia.com/app/20120004726#b

http://www.heightquest.com/2012/02/does-bone-mineral-density-affect-height.html

http://www.naturalheightgrowth.com/2013/10/31/bmpr1a-may-key-form-new-growth-plates/

http://www.naturalheightgrowth.com/wp-content/uploads/2012/12/ElbowLoading.pdf

http://www.naturalheightgrowth.com/2012/11/19/10-scientific-papers-on-the-human-growth-process-and-mechanics-the-reader-should-definitely-read/

[F_99]

The only between rats and us is that their growth plates never close. I don't know if it's the same for rabbits.

Yes. He mentioned we should use rabbits because their growth plates close due to sxx hormones (unlike rats) similarly to human's.

Also I asked him if this:

3. 8-Nitro-cGMP promotes bone growth through expansion of growth plate cartilage
https://www.sciencedirect.com/science/article/abs/pii/S0891584917305956?via%3Dihub

could help adults grow taller; and he said "yes, but you would likely get more results from those who have open growth plates with 9NCamp".

If you find out more about it, let me know.

Also, this guy is doing the Kojima method? https://www.tapatalk.com/groups/lsjl/my-shinbones-routine-based-on-kojima-and-skyheight-t1051.html

And Tyler is still going http://www.limblengtheningforum.com/index.php?topic=65630.0
but we need X-ray results. https://www.tapatalk.com/groups/lsjl/modified-lsjl-update-method-t1032-s110.html