Sorry, I forgot to adress your other concern. Generally, with good, skilled and experienced doctors, in cooperation with the patient, infections are less frequent and easily treated.
When things get worse, a suplementary surgery may be needed.
If very very very bad luck with infection by multiresistant bacteria in a badly managed hospital and a bad doctor, things may get out of control, and then amputation may be needed. But this is theoretically, I have never heard of such a case in CLL. Infection., we all know may be lethal but It's one of the less serious dangers, in general terms, when compared to others, in CLL.