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[TheMagicalBlueEye]

As I know this forum gathers people of different backgrounds. What do you think about it? Do you think advancements in tissue engineering and stem cells science will one day (in foreseeable future) create a sound alternative to LL?

[wannagrowtaller]

Maybe it is possible to create bone tissue, but what about soft tissue?

[StrangeDays67]

Its possible. It could also help develop spine lengthening, which is a good alternative for us who have short torsos

[shortguy4cll]

Its already been done.

[TheMagicalBlueEye]

Its already been done.

Well, my brother-in-law (sister's husband) is a PhD in chemistry material science (he's doing research on synthetic scaffolds used to grow tissue), but I have never asked him about such subject.

[Antoine]

What do you think about this? https://m.medicalxpress.com/news/2018-10-skeletal-stem-cells-regress-tasked.html
IMHO, this passage is interesting: “Now that we’ve identified one of the molecular pathways responsible for this developmental shift, it may be possible to target the proteins in that pathway to achieve a similar outcome without the requirement for physical force”.
Are we closer to a limb lengthening technique without surgery?
I think shorter people should unite and expect the problem finally to be solved.

[myloginacc]

What do you think about this? https://m.medicalxpress.com/news/2018-10-skeletal-stem-cells-regress-tasked.html
IMHO, this passage is interesting: “Now that we’ve identified one of the molecular pathways responsible for this developmental shift, it may be possible to target the proteins in that pathway to achieve a similar outcome without the requirement for physical force”.
Are we closer to a limb lengthening technique without surgery?
I think shorter people should unite and expect the problem finally to be solved.

Thank you very much for sharing.

The finding has provocative clinical implications, the researchers believe.

"Now that we've identified one of the molecular pathways responsible for this developmental shift, it may be possible to target the proteins in that pathway to achieve a similar outcome without the requirement for physical force," Carter said.

Everything is right in front of us.

We need to get investors to see how much people are paying doctors like Paley just to get taller, despite the pain levels and months you stay crippled. Whatever biotech company develops a way to make people taller is going to become a fortune 500 company.

[Antoine]

I agree. I hope stem cells will lengthen bones without breaking them soon.

[TheMagicalBlueEye]

What do you think about this? https://m.medicalxpress.com/news/2018-10-skeletal-stem-cells-regress-tasked.html
IMHO, this passage is interesting: “Now that we’ve identified one of the molecular pathways responsible for this developmental shift, it may be possible to target the proteins in that pathway to achieve a similar outcome without the requirement for physical force”.
Are we closer to a limb lengthening technique without surgery?
I think shorter people should unite and expect the problem finally to be solved.

I'm not a pharmaceutical or medical scientist but I have always wanted to kick-start a company that offers some revolutionary cosmetic therapies based on recent scientific advancements. But I know that a sheer number of regulatory red-tape  could kill any newbie business in this field.

[TheMagicalBlueEye]

What do you think about this? https://m.medicalxpress.com/news/2018-10-skeletal-stem-cells-regress-tasked.html
IMHO, this passage is interesting: “Now that we’ve identified one of the molecular pathways responsible for this developmental shift, it may be possible to target the proteins in that pathway to achieve a similar outcome without the requirement for physical force”.
Are we closer to a limb lengthening technique without surgery?
I think shorter people should unite and expect the problem finally to be solved.

I'm trying to find their article in scientific journal for more information. I have some level of expertise in mathematical statistics and scientific method so understanding their experiment from methological point of view wouldn't be a problem to me, yet I know very little about biochemistry or about ways molecular pathways influence each other, otherwise I hope I could learn something new by reading it. Maybe it's just a journalist reporting hype, I hope it's not.

[Ghostfish]

I'm trying to find their article in scientific journal for more information. I have some level of expertise in mathematical statistics and scientific method so understanding their experiment from methological point of view wouldn't be a problem to me, yet I know very little about biochemistry or about ways molecular pathways influence each other, otherwise I hope I could learn something new by reading it. Maybe it's just a journalist reporting hype, I hope it's not.

Hi TMBE
Please the other thread which is basically same as yours. Although stem cells for limb lengthening sound fancy and interesting, it is unlikely to happen in any near future.  It is not because of difficulty of stem cell usage for bone growth but because of technical limit for generating a proper gap for limb lengthening.   
http://www.limblengtheningforum.com/index.php?topic=15836.0

[Antoine]

OK, but in this case we’re talking about stem cells that lengthen bones without needing to break the bones and create any gap. TheMagicalBlueEye please let us know if you discover something new. If this could come true, it would be a huge breakthrough.

[Antoine]

This article seems important too: https://www.regenexx.com/blog/skeletal-stem-cells-found-living-in-the-growth-plates-may-one-day-make-us-taller/
“this new discovery could both add another tool for regenerative medicine specialists to use to help heal orthopedic damage and new ways to solve short stature”.
We need some guinea pigs and investors here.